Chicken Alfredo Lasagna

chicken alfredo lasagna beauty image

The Spruce Eats / Morgan Walker

  • Total: 55 mins
  • Prep: 20 mins
  • Cook: 35 mins
  • Servings: 10 slices
  • Yield: 1 pan

There is something so nostalgic about pasta dishes in general, but lasagna specifically holds a special place in the hearts of many. For when you're looking to switch up your lasagna routine, here is a great alternative to the traditional. This recipe takes the well-known elements of Chicken Fettuccine Alfredo and morphs them into a delicious lasagna.  

Enjoy it as a weeknight meal that comes together in less than an hour, or prepare the dish ahead of time and freeze it for baking later. Just be sure to assemble the lasagna in a disposable aluminium baking dish, cover the assembled lasagna dish tightly with foil, and store inside a large freezer bag in the freezer for up to three months. Thaw in the fridge when ready to eat and bake according to recipe instructions!

Ingredients

  • 2 tablespoons unsalted butter
  • 2 garlic cloves, minced
  • 1 small yellow onion, chopped
  • 8 ounces cremini mushrooms, sliced
  • 10 ounces fresh baby spinach
  • 3 cups whole milk
  • 1 1/2 cup grated Parmesan cheese
  • 15 ounces ricotta cheese
  • 1 tablespoon dried parsley
  • 3 cups shredded rotisserie chicken
  • 4 ounces thinly sliced pancetta, cut into strips and cooked
  • 3 ounces thinly sliced prosciutto or deli ham, cut into strips and cooked
  • 9 ounces oven-ready lasagna noodles
  • 3 cups shredded mozzarella cheese
  • 3 to 4 basil leaves, for garnish

Steps to Make It

  1. Gather the ingredients. Preheat the oven to 350 F.

    alfredo lasagna ingredients
     The Spruce Eats / Morgan Walker
  2. In a large skillet over medium-high heat add butter, garlic, and onion and cook for 2 to 3 minutes or until the onion becomes translucent.

    saute onions and mushrooms
     The Spruce Eats / Morgan Walker
  3. Add the spinach and 1 tablespoon of water and stir until it wilts about 1 minute.

    saute spinach with onions and mushrooms
     The Spruce Eats / Morgan Walker
  4. Add milk, Parmesan, ricotta, and parsley. Salt and pepper to taste and stir until incorporated.

    add milk and cheese to spinach, onion, mushroom mixture
     The Spruce Eats / Morgan Walker
  5. Raise heat to high and heat, stirring occasionally until the mixture comes to a slight simmer and begins to thicken, about 8 minutes. Remove from heat and stir in chicken. 

    add shredded chicken to creamy spinach and mushroom mixture
     The Spruce Eats / Morgan Walker
  6. In a 9 x 13-inch baking dish add a large spoonful of the chicken Alfredo mixture. Layer with noodles, Alfredo mixture, sliced pancetta and prosciutto, then one-third of the shredded mozzarella cheese. Repeat with the remaining ingredients.

    layered pasta, alfredo mixture, pancetta, prosciutto for lasagna
     The Spruce Eats / Morgan Walker
  7. Cover the lasagna with foil and bake for 35 to 35 minutes. Remove foil and broil for 2 to 3 minutes or until cheese is slightly browned and bubbling.

    browned and finished chicken alfredo lasagna
    The Spruce Eats / Morgan Walker 
  8. Top with fresh basil and serve hot!

Glass Bakeware Warning

Do not use glass bakeware when broiling or when a recipe calls to add liquid to a hot pan, as glass may explode. Even if it states oven-safe or heat resistant, tempered glass products can, and do, break occasionally.


For premade casseroles or leftovers that are in a glass baking dish and have been refrigerated, do not place directly into a hot oven as the glass can shatter. Instead, place any cold glass bakeware into a cold oven to warm up while it preheats. Or, allow the bakeware to rest outside of the fridge for 30 minutes to reach room temperature while the oven preheats.