Chicken Manicotti

chicken manicotti in a baking dish

The Spruce Eats / Leah Maroney 

  • Total: 2 hrs
  • Prep: 30 mins
  • Cook: 90 mins
  • Servings: 6 servings
Nutritional Guidelines (per serving)
670 Calories
26g Fat
57g Carbs
51g Protein
See Full Nutritional Guidelines Hide Full Nutritional Guidelines
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Nutrition Facts
Servings: 6
Amount per serving
Calories 670
% Daily Value*
Total Fat 26g 34%
Saturated Fat 8g 42%
Cholesterol 115mg 38%
Sodium 322mg 14%
Total Carbohydrate 57g 21%
Dietary Fiber 6g 21%
Protein 51g
Calcium 239mg 18%
*The % Daily Value (DV) tells you how much a nutrient in a food serving contributes to a daily diet. 2,000 calories a day is used for general nutrition advice.
(Nutrition information is calculated using an ingredient database and should be considered an estimate.)

This simple five ingredient pasta casserole recipe for Chicken Manicotti tastes like you spent all day making it. Chicken and spinach alfredo manicotti is creamy, filling, and sneaks in your green vegetables! It’s super easy to make and is so full of flavor. The alfredo sauce is homemade, but it comes together in only a few steps and is so creamy and garlicky. We used leftover rotisserie chicken to speed up the process. Feel free to use any leftover chicken you have. Or you can grill or poach the chicken prior to preparing this recipe. 


You can easily make this dish vegetarian by leaving out the chicken, simply increase the amount of spinach and ricotta cheese so you have enough to fill all of the noodles. 


Try splitting this dish into two containers and freezing one before baking. Once you’re ready to eat, serve it alongside your favorite salad and some breadsticks, for sopping up the delicious sauce.

Ingredients

  • For the Noodles and Filling:
  • 14 manicotti noodles
  • 3 cups rotisserie chicken (shredded)
  • 2 cups spinach (chopped)
  • 1 small onion (diced)
  • 1 clove garlic
  • 1 ½ cups mozzarella cheese (divided)
  • ¾ cup parmesan cheese (grated)
  • 1 teaspoon Italian seasoning
  • 1 teaspoon salt
  • ½ teaspoon ground black pepper
  • 2 cups ricotta cheese
  • For the Alfredo Sauce:
  • 4 tablespoons butter
  • 2 cloves garlic (minced)
  • ¼ cup flour
  • 1 ½ cup chicken broth
  • 4 ounces cream cheese
  • 1 cup cream
  • ½ cup parmesan cheese
  • 1 teaspoon salt
  • ½ teaspoon ground black pepper
  • For garnish: parsley

Steps to Make It

Prepare the noodles and filling.

  1. Gather your ingredients.

    chicken manicotti ingredients on a marble board
  2. Boil the manicotti noodles until al dente, about 6 minutes, depending on the brand. Drain and place on a parchment-lined baking sheet to cool. Do not leave in a colander; the noodles will become misshapen and hard to work with.

    cooked manicotti noodles on a baking sheet
  3. Add the cooked chicken, spinach, onion, garlic, ¾ cup mozzarella cheese, parmesan cheese, and seasonings to a food processor. Process until it forms small shreds and is completely combined.

    pureed chicken and spinach in a food processor
  4. Stir the chicken mixture into the ricotta mixture until completely incorporated. Taste and add salt if needed. It should be highly seasoned since it will be served inside the manicotti noodles.

    manicotti filling in a large bowl
  5. Add the filling to a large piping bag and cut the end off so it will fit comfortably into the opening of the manicotti noodles. Pipe the filling into each noodle so that it completely fills each noodle. Cover and set aside while you prepare the sauce. 

    manicotti noodles filled with chicken filling

Prepare the sauce.

  1. Gather your ingredients.

    ingredients for Alfredo sauce on a marble board
  2. Preheat the oven to 375F.

    Melt the butter in a large pan or pot on medium-high heat. Whisk in the flour and garlic until incorporated with the butter. Allow it to cook for another minute to cook off some of the flour taste.

    flour and butter cooking in a saucepan
  3. Gradually whisk in the chicken broth, cream, cream cheese, parmesan cheese and heat for 3 to 5 minutes or until slightly thickened and the sauce is smooth. Add salt and pepper and then taste. Add more if needed.

    Alfredo sauce cooking in a pot
  4. Put a layer of the sauce into the bottom of your 9 by 13 inch baking dish. Add the noodles on top of the sauce.

    manicotti noodles in a baking dish
  5. Cover with the remaining sauce, trying to cover the noodles as much as possible. Sprinkle with remaining mozzarella cheese, cover and bake for 15 to 20 minutes or until bubbly and heated through.

    manicotti noodles in a baking dish covered in sauce and cheese
  6. Remove the foil and broil until the top is lightly browned.

    Allow to cool for a few minutes and then serve. This dish goes well with breadsticks and a side salad.

    chicken manicotti browned from the oven

Glass Bakeware Warning

Do not use glass bakeware when broiling or when a recipe calls to add liquid to a hot pan, as glass may explode. Even if it states oven-safe or heat resistant, tempered glass products can, and do, break occasionally.


For premade casseroles or leftovers that are in a glass baking dish and have been refrigerated, do not place directly into a hot oven as the glass can shatter. Instead, place any cold glass bakeware into a cold oven to warm up while it preheats. Or, allow the bakeware to rest outside of the fridge for 30 minutes to reach room temperature while the oven preheats.

Recipe Tips

Cook the noodles very al dente so they don't fall apart when stuffing with the filling and when cooking.

You can make the sauce ahead of time and store in the refrigerator until you are ready to bake.

You can freeze this dish in the freezer for up to 3 months. Simply defrost in the refrigerator before you bake.

Recipe Variations

You can replace the alfredo sauce with your favorite marinara sauce. It’s just as delicious and has fewer calories.