Chicken Pepperoni Bake: Pizza in a Casserole

  • 55 mins
  • Prep: 15 mins,
  • Cook: 40 mins
  • Yield: 8 servings
Ratings (4)

This easy recipe uses pepperoni, mozzarella cheese, tomatoes, and herbs to spice up chicken breasts. If you think this sounds a lot like pizza, you're right. Pizza sans crust, that is. It's comfort food for sure, with an Italian twist.

This recipe is from the book "At Home in the Kitchen" by Jorj Morgan.

What You'll Need

  • For the Chicken:
  • 4 chicken breasts (skinless, boneless; 6 ounces each)
  • 3 tablespoons olive oil
  • 1/2 cup breadcrumbs
  • 1 teaspoon oregano
  • 1/2 teaspoon garlic powder
  • salt to taste
  • black pepper to taste
  • For the Sauce:
  • 1 can/16 ounces tomatoes (chopped)
  • 1 teaspoon sugar
  • 1 teaspoon oregano
  • 1/2 teaspoon basil
  • 1/2 teaspoon garlic powder
  • salt to taste
  • black pepper to taste
  • For the Topping:
  • 2 ounces pepperoni (sliced into thin rounds; 8 slices)
  • 1/2 cup mozzarella cheese (shredded)

How to Make It

Prepare the Chicken Breasts

  1. Preheat the oven to 350 F.
  2. Pound the chicken breast halves between two sheets of plastic wrap to a thickness of about 1/2 inch.
  3. In a shallow skillet, heat the olive oil over medium-high heat.
  4. In a bowl, combine the breadcrumbs with the oregano and garlic powder. Season the mixture with salt and freshly ground pepper.
  5. Coat the chicken breasts with the breadcrumbs.
  6. Saute the chicken breasts in the olive oil until browned, about 4 minutes on each side.
  1. Remove the chicken to a baking dish and set aside.

Make the Sauce

  1. In a saucepan, combine the tomatoes, sugar, oregano, basil and garlic powder.
  2. Cook over medium heat for 10 minutes.
  3. Season with salt and freshly ground pepper.

Assemble and Bake the Casserole

  1. Pour the sauce over the browned chicken in the baking pan.
  2. Place the slices of pepperoni on top of each chicken breast and sprinkle the tops with mozzarella cheese.
  3. Bake for 20 to 30 minutes or until the cheese melts and just begins to brown.


Serving Suggestions
Since this is sort of like eating chicken and pepperoni pizza without the crust, you need a starch to round it out. Pasta tossed in butter with sauteed onions and mushroom, garnished with parsley, is a good option. Or just a simple side of spaghetti tossed in olive oil and garlic is a tasty complement. Add garlic bread (more carbs, but this is Italian night) and an Italian green salad with lettuce, artichoke hearts, red onion and Parmesan with vinaigrette dressing to round out the meal.

Wash this all down with a dry white wine (it's chicken) like Orvieto or pinot grigio. If you prefer red wine, you can feel good about going that direction since this might be chicken, but it is in tomato sauce and then there's the pepperoni. So go ahead and indulge in a Chianti, barbera, Valpolicella or Montepulciano.

Nutritional Guidelines (per serving)
Calories 301
Total Fat 18 g
Saturated Fat 5 g
Unsaturated Fat 9 g
Cholesterol 76 mg
Sodium 229 mg
Carbohydrates 8 g
Dietary Fiber 1 g
Protein 25 g
(The nutrition information on our recipes is calculated using an ingredient database and should be considered an estimate. Individual results may vary.)