Muffaletta Sandwich

Muffaletta sandwich

The Spruce

Prep: 10 mins
Cook: 0 mins
Total: 10 mins
Servings: 4 servings
Nutrition Facts (per serving)
760 Calories
64g Fat
16g Carbs
33g Protein
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Nutrition Facts
Servings: 4
Amount per serving
Calories 760
% Daily Value*
Total Fat 64g 82%
Saturated Fat 19g 97%
Cholesterol 99mg 33%
Sodium 2562mg 111%
Total Carbohydrate 16g 6%
Dietary Fiber 3g 11%
Total Sugars 2g
Protein 33g
Vitamin C 3mg 15%
Calcium 430mg 33%
Iron 3mg 19%
Potassium 382mg 8%
*The % Daily Value (DV) tells you how much a nutrient in a food serving contributes to a daily diet. 2,000 calories a day is used for general nutrition advice.
(Nutrition information is calculated using an ingredient database and should be considered an estimate.)

Just like beignets and gumbo, the muffaletta is a quintessential part of New Orleans cuisine. Many people had their first experience with the iconic sandwich at Central Grocery on Decatur Street. Central Grocery opened its doors in the heart of the French Quarter in 1906. Its first owner was Salvatore Lupo, a Sicilian sandwich-maker who came up with the legendary muffaletta. The sandwich became an easier way to serve farmers who would stop by for a traditional Sicilian lunch where everything (cold cuts, cheese, bread) was eaten separately, so Lupo sliced open a whole loaf of his Sicilian sesame bread and stuffed everything inside.

There are many ways to make it at home, but this comes as close to the real thing as possible. A whole muffaletta is served on a round loaf of bread about eight inches in diameter and fully two-inches tall. Bread not included, the sandwich weighs in at almost two pounds! Eating a whole sandwich in one sitting seems impossible and, in fact, Central Grocery sells half- and quarter-sandwiches for that reason.

The key ingredient is the olive salad mix. Ideally, you want to make the sandwich an hour or two before eating it so the juices from the olive mix can soak into the bread, which makes this a perfect picnic dish. You can make a loaf of muffaletta bread at home, but a purchased round Italian loaf will do nicely in a pinch.


  • 1 (8-inch) round loaf muffuletta bread, or loaf Italian bread

  • 1 cup olive salad mix

  • 1/4 pound sliced ham

  • 1/4 pound sliced mortadella

  • 1/4 pound sliced Genoa salami

  • 1/4 pound sliced provolone

  • 1/4 pound sliced mozzarella

Steps to Make It

  1. Gather the ingredients.

    Ingredients for muffaletta sandwich
    The Spruce
  2. Cut round bread loaf in half horizontally.

    Cut bread loaf into half
    The Spruce
  3. Spread half the bottom portion with olive salad mix, then layer on meats and cheeses.

    Spread olive mix
    The Spruce
  4. Cover with top of the bread. Ideally, the sandwich should be made an hour or more in advance and then tightly wrapped in plastic wrap to enable the juices to soak into the bread.

    Cover with bread
    The Spruce 
  5. Slice into quarters and serve.

    Cut into fours
    The Spruce
  6. Enjoy!


  • Appetizer- or canapé-sized versions of this recipe can be made on slices of baguette.