Quick and Easy Cajun Chicken Pasta

Spicy Cajun chicken and pasta recipe

​The Spruce / Julia Hartbeck

  • Total: 35 mins
  • Prep: 20 mins
  • Cook: 15 mins
  • Yield: 6 servings
Nutritional Guidelines (per serving)
701 Calories
38g Fat
54g Carbs
36g Protein
See Full Nutritional Guidelines Hide Full Nutritional Guidelines
Nutrition Facts
Servings: 6 servings
Amount per serving
Calories 701
% Daily Value*
Total Fat 38g 49%
Saturated Fat 19g 96%
Cholesterol 146mg 49%
Sodium 314mg 14%
Total Carbohydrate 54g 20%
Dietary Fiber 5g 17%
Protein 36g
Calcium 184mg 14%
*The % Daily Value (DV) tells you how much a nutrient in a food serving contributes to a daily diet. 2,000 calories a day is used for general nutrition advice.
(Nutrition information is calculated using an ingredient database and should be considered an estimate.)

This Cajun chicken and pasta skillet dish is quick and easy to prepare. It's made with diced cooked chicken, spicy Cajun seasonings and cayenne pepper, tomatoes, Parmesan cheese, and a variety of vegetables. Enjoy this flavorful chicken pasta dish with a salad and cornbread or biscuits. Use fusilli, rotini, or similar pasta in this easy recipe.


  • 12 ounces or fusilli or rotini pasta
  • 2 tablespoons butter
  • 8 ounces fresh mushrooms (sliced)
  • 1 red bell pepper (sliced)
  • 1 green bell pepper (sliced)
  • 6 green onions (thinly sliced)
  • 3 cloves garlic (minced)
  • 3 to 4 cups diced cooked chicken
  • 1 1/2 tablespoons Cajun seasoning
  • 3/4 teaspoon cayenne pepper
  • 3/4 teaspoon ground black pepper
  • 1 (10.75-ounce) can cream of mushroom soup
  • 1/4 cup milk
  • 1 (14.5-ounce) can diced tomatoes
  • 1/2 cup grated Parmesan cheese (plus more for sprinkling)

Steps to Make It

  1. Gather the ingredients.

    Ingredients for spicy Cajun chicken and pasta
    ​The Spruce / Julia Hartbeck
  2. Cook the pasta in boiling salted water following package directions. Drain in a colander, and rinse well with hot water.

    Cook the pasta
    ​The Spruce / Julia Hartbeck
  3. In a large skillet over medium heat, saute the mushrooms and sliced red and green bell pepper until the vegetables are tender and mushrooms are lightly browned.

    Peppers and mushrooms
    ​The Spruce / Julia Hartbeck
  4. To the mushroom mixture, add the sliced green onions, minced garlic, and chicken; cook, stirring constantly, for 1 minute.

    Add sliced green onions
    ​The Spruce / Julia Hartbeck
  5. Stir in the Cajun seasoning, cayenne pepper, and black pepper; cook, stirring, for another minute.

    Stir in Cajun seasoning
    ​The Spruce / Julia Hartbeck
  6. Add the soup, milk, and tomatoes. Bring to a simmer.

    Add soup, milk, tomatoes
    ​The Spruce / Julia Hartbeck
  7. Stir in the grated Parmesan cheese and the cooked pasta. Heat through and serve.

    Stir in Parmesan cheese
    ​The Spruce / Julia Hartbeck